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Review Article
Controversy in use of mannitol in head injury
Abrar Ahad Wani M Ch, Altaf U Ramzan M Ch, Furqan Nizami MS Nayil K Malik
M Ch, A R Kirmani MS, AR Bhatt M Ch, Sarabjeet Singh M Ch
Department of Neurosurgery Sher-i- Kashmir Institute of Medical Sciences,
Srinagar
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The most commonly used drug in the patients of severe head injury
is mannitol. The drug is classified pharmacologically as osmotic-diuretic
but its mechanism of action in decreasing intracranial pressure
is multi-factorial. Despite having dramatic results in the management
of head injury patients the drug is still facing many controversies
ranging from mechanism of action to the efficacy, especially is
the light of evidence based medicine.
Keywords : head injury, mannitol
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Address for correspondence:
Dr. Abrar Ahad Wani
Assistant Professor: Department of Neurosurgery,
Sher-i- Kashmir Institute of Medical Sciences Srinagar,
J&K. India
E-mail: abrarwani@rediffmail.com
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